- Title
- Physico-chemical properties and reactive oxygen species generation by respirable coal dust: implication for human health risk assessment
- Creator
- Zazouli, Mohammad Ali; Dehbandi, Reza; Mohammadyan, Mahmoud; Aarabi, Mohsen; Dominguez, Ana Oliete; Kelly, Frank J.; Khodabakhshloo, Nafise; Rahman, Mohammad Mahmudur; Naidu, Ravi
- Relation
- Journal of Hazardous Materials Vol. 405, Issue 5 March 2021, no. 124185
- Publisher Link
- http://dx.doi.org/10.1016/j.jhazmat.2020.124185
- Publisher
- Elsevier
- Resource Type
- journal article
- Date
- 2021
- Description
- This study investigates the mineralogy, micro-morphology, chemical characteristics and oxidation toxicity of respirable dusts generated in underground coal mines. The active sampling was applied to collect airborne particulates with aerodynamic diameter <4 µm (PM4) at depth greater than 500 m from earth surface. The average mass concentration of PM4 was extremely higher than recommended values. QXRD and FESEM-EDS analyses were applied to study the micro-mineralogy and micro-morphology of respirable dusts. The chemical analysis by ICP-MS revealed an enrichment of V, Cr, Cu, Zn, As, Ag, Cd and Sb in respirable dust compared with the background environment and world coals. The EPA’s health risk model showed that the health risk posed by Cr and Co in all workplaces exceeded the acceptable risk value for human health. The synthetic respiratory tract lining fluid (RTLF) model was utilized to achieve a novel insight into the toxicity of respirable coal dust. The result showed an overall depletion of lung surface antioxidants with the decreasing trend of ascorbic acid > reduced glutathione >> urate, implying low- to medium level of oxidative stress. The result of this study can be applied globally by decision-makers to decrease hazardous exposure of mine workers to respirable dust.
- Subject
- respirable dust; coal mine; oxidative potential; toxic elements
- Identifier
- http://hdl.handle.net/1959.13/1434744
- Identifier
- uon:39491
- Identifier
- ISSN:0304-3894
- Language
- eng
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